Denny gets a disturbing prognosis about the progression of his disease; Catherine Piper returns; Jerry and Katie take on the case of a student fighting to keep her acceptance to Harvard.
Shirley's intimate Thanksgiving dinner with Carl Sack turns into a dysfunctional family affair when she invites Alan, Denny, Jerry, Katie, Edwin, and his 6-year-old foster son to join them.
Alan goes to the Supreme Court to get Denny access to a non-FDA approved drug to slow the progression of his Alzheimer's.
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