Cristina, back from her honeymoon trip, searches in vain for Burke; Meredith, Cristina, Izzie and Alex spend their first day as residents with their own groups of interns.
Cristina and Burke's wedding day arrives; the interns get their exam results; the chief's successor; Callie and George make a decision about their relationship.
The residents and interns treat the victims of a massive explosion at an apartment building; Mama Burke returns to collect her son's things; Lexie tries to have a heart-to-heart with unwilling Meredith.
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