The attendings are extra-attentive to a patient, who is the chairman of the hospital board; Cristina helps Burke plan the wedding.
Izzie faces her past and finds comfort in George; Alex has an attachment to Jane Doe; Meredith and Derek question their status; Cristina resolves to fight for her relationship with Burke.
Addison takes a temporary leave from Seattle Grace and visits old friends in Los Angeles; Cristina reluctantly plans her wedding with help from Burke's mother (Diahann Carroll) and her own; Derek must perform emergency surgery on Jane Doe.
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