Everyone tries to help Callie and her baby recover; the sudden death of a clinical trial patient impacts Derek and Meredith in different ways; Teddy is surprised by a familiar face.
A cataclysmic event leaves the doctors shaken; Callie, on the verge of a life-changing moment, starts imagining about the hospital and her friends.
Callie and Arizona's wedding is not coming together as they hoped it would; Alex seems to be the first choice for chief resident; Meredith and Derek make a life-changing decision; Dr. Perkins tempts Teddy with a proposition.
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