The residents and interns treat the victims of a massive explosion at an apartment building; Mama Burke returns to collect her son's things; Lexie tries to have a heart-to-heart with unwilling Meredith.
Cristina, back from her honeymoon trip, searches in vain for Burke; Meredith, Cristina, Izzie and Alex spend their first day as residents with their own groups of interns.
George's skill level dazzles the new interns; Meredith halfheartedly helps Lexie with her first emergency patient.
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