Meredith and Derek's relationship concerns Zola's adoption counselor; Alex notices he has become an outcast; Cristina makes a difficult decision.
While Meredith faces the repercussions of messing with the medical trial, April tries to step up as chief resident; Cristina and Owen disagree.
The chief makes a decision that shocks everyone at Seattle Grace; Owen and Cristina attempt to find normalcy; April struggles in her new role; the fifth-year residents receive their first solo surgery assignments.
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