Meredith finally tells Derek about her pregnancy and miscarriage; during a surgery, Cristina experiences PTSD; Bailey won't let Alex operate until he has the bullet in his chest removed.
The staff tries to deal with physical and emotional trauma in the wake of the vengeful gunman's deadly rampage; Derek makes a spontaneous decision to resign as chief and return to surgery.
Issues surface when Derek's estranged sister, Amelia (Caterina Scorsone), visits unexpectedly; Meredith and Derek continue to try to ease Cristina back into surgery.
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