Issues surface when Derek's estranged sister, Amelia (Caterina Scorsone), visits unexpectedly; Meredith and Derek continue to try to ease Cristina back into surgery.
Meredith finally tells Derek about her pregnancy and miscarriage; during a surgery, Cristina experiences PTSD; Bailey won't let Alex operate until he has the bullet in his chest removed.
Derek and Meredith visit the obstetrician and receive disturbing news; Lexie notices April and Meredith growing closer; Jackson tries to get ahead in the operating room.
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