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The interns take their first-year medical exams; the residents attend to three injured mountain-climbers; Callie's suspicions of George and Izzie grow; Cristina struggles to write her wedding vows.
Addison takes a temporary leave from Seattle Grace and visits old friends in Los Angeles; Cristina reluctantly plans her wedding with help from Burke's mother (Diahann Carroll) and her own; Derek must perform surgery on Jane Doe.
Cristina and Burke's wedding day arrives; the interns get their exam results; the chief's successor; Callie and George make a decision about their relationship.
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