The chief's wife rushes their niece to Seattle Grace; Izzie gets an unexpected reaction when she reveals her feelings about George to a mutual friend; Derek shows Cristina how to be a better teaching resident; Norman misdiagnoses a problem.
George's skill level dazzles the new interns; Meredith halfheartedly helps Lexie with her first emergency patient.
Halloween is full of surprises for the doctors of Seattle Grace; Alex receives an unexpected visit from a former patient; Meredith thinks her mother's ashes are haunting her; a surgeon Cristina admires snubs her.
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