House takes matters into his own hands when he feels certain that one of the actors on his favorite soap opera (Jason Lewis) is suffering from a serious medical condition, but the actor dismisses House's assessment.
House suspects a patient has a bigger problem than the original diagnosis; House and Amber argue about how much time they each get to spend with Wilson; Cuddy demands that House give his team performance reviews.
A bus accident robs House of several hours, and as his memory slowly returns, he realizes that one of his fellow passengers was exhibiting signs of a deadly illness, so he races to unlock the secrets in his brain.
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