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A 16-year-old chess prodigy with intense head pain and behavioral issues offends the members of House's team during his treatment.
A 19-year-old college student goes to the hospital after coughing up blood during karate class; House takes a special interest in an attractive nutritionist (Piper Perabo), who accompanied her boyfriend to the clinic.
The team takes on the case of a woman who was rescued at sea en route from Cuba in her desperate bid to get a diagnosis from Dr. House.
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