House's murky memories of the bus crash test his friendship with Wilson and threaten to change their lives forever.
A bus accident robs House of several hours, and as his memory slowly returns, he realizes that one of his fellow passengers was exhibiting signs of a deadly illness, so he races to unlock the secrets in his brain.
Still mourning the death of his girlfriend, Wilson resigns from Princeton Plainsboro; House must determine if he is responsible for the death of his best friend's girlfriend; Thirteen struggles to treat a patient objectively.
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